TOPIC：New Aspects of Enantioselective Catalysis by Chiral Brønsted Acids and Bases 
SPEAKER：Professor Masahiro Terada ，日本东北大学

TIME：May 30 (Monday)PM15:30  
LOCATION：Room 528, Chemistry Building A (化学A楼528演讲厅) 
INVITER： 张万斌教授
 

演讲人简介：

Masahiro Terada

Department of Chemistry,

Graduate School of Science,

Tohoku University, Aoba-ku, Sendai 980-8578, Japan

Tel: 81-22-795-6602

Fax: 81-22-795-6584

Email: mterada@m.tohoku.ac.jp

Homepage: http://www.orgreact.sakura.ne.jp/index.html

Educational Background

1982       B. Eg.       Dept. of Applied Chemistry, Tokyo Institute of Technology

1988       M. Eg.     Dept. of Applied Chemistry, Tokyo Institute of Technology

1993       Ph. D,       Dept. of Applied Chemistry, Tokyo Institute of Technology

1999-2000              Postdoctoral research with Professor Matthew Shair at Harvard University, US

Professional Career

1989-2001 Assistant Professor, Faculty of Engineering, Tokyo Institute of Technology

2001-2006   Associate Professor, Graduate School of Science, Tohoku University

2006-present Professor, Graduate School of Science, Tohoku University

2011.7-present Head Investigator of Scientific Research on Innovative Areas ‘Advanced Molecular Transformations by Organocatalysts’.

Research Interests

Our current research interests are focused on the development of new and useful synthetic methodologies based on the design of novel chiral Brønsted acid and base catalysts as well as the utilization of transition metal catalysts.

Awards

2003, Incentive Award in Synthetic Organic Chemistry, Japan

2008, The Chemical Society of Japan Award for Creative Work

2010, The Mukaiyama Award

2011, Daiichi-Sankyo Award for Medicinal Organic Chemistry

2012, Nagoya Silver Medal

2015, Molecular Chirality Award 2015

Selected Recent Publications

(1) “Construction of Vicinal Quaternary Stereogenic Centers by Enantioselective Direct Mannich-Type Reaction Using a Chiral Bis(guanidino)iminophosphorane Catalyst”, Tadahiro Takeda, A. Kondoh, M. Terada, Angew. Chem. Int. Ed., 2016, 55, 4734-4737.

(2) “Enantioselective Aza Michael-type Addition to Alkenyl Benzimidazoles Catalyzed by Chiral Phosphoric Acid” Y.-Y. Wang, K. Kanomata, T. Korenaga, M. Terada, Angew. Chem. Int. Ed. 2016, 55, 927-931.

(3) “Chiral Brønsted Acid-Catalyzed Enantioselective Friedel-Crafts Reaction of 2-Methoxyfuran with Aliphatic Ketimines Generated in Situ” A. Kondoh, Y. Ota, T. Komuro, F. Egawa, K. Kanomata, M. Terada, Chem. Sci. 2016, 7, 1057-1062.

(4) “Enantioselective Addition of a 2-Alkoxycarbonyl-1,3-dithiane to Imines Catalyzed by a Bis(guanidino)iminophosphorane Organosuperbase” A. Kondoh, M. Oishi, T. Takeda, M. Terada, Angew. Chem. Int. Ed. 2015, 54, 15836-15839.

(5) “Ring Expansion of Epoxides under Brønsted Base Catalysis: Formal [3+2] Cycloaddition of β,γ-Epoxy Esters with Imines Providing 2,4,5-Trisubstituted 1,3-Oxazolidines” A. Kondoh, K. Odaira, M. Terada, Angew. Chem. Int. Ed. 2015, 54, 11240-11244.

(6) “Skeletal Rearrangement of O-Propargylic Formaldoximes by a Gold-Catalyzed Cyclization/Intermolecular Methylene Transfer Sequence” I. Nakamura, S. Gima, Y. Kudo, M. Terada, Angew. Chem. Int. Ed. 2015, 54, 7154-7157.

(7) “Kinetic Resolution of Racemic Amino Alcohols through Intermolecular Acetalization Catalyzed by Chiral Brønsted Acid” T. Yamanaka, A. Kondoh , M. Terada, J. Am. Chem. Soc. 2015, 137, 1048-1051.